M. Nedim Ince, MD
Clinical Associate Professor of Internal Medicine
Gastroenterology and Hepatology
Welcome
Dr. Ince's clinical interests include general gastroenterology with particular interest in inflammatory bowel disease. His research focuses on helminthic regulation of intestinal inflammation. His laboratory investigates the role of T helper 2 and TGF-beta signaling pathways in helminthic mucosal immune modulation. His group uses graft vs. host disease and inflammatory bowel disease preclinical models.
Recent Publications
Li Y, Guan X, Liu W, Chen HL, Truscott J, Beyatli S, Metwali A, Weiner GJ, Zavazava N, Blumberg RS, Urban JF Jr, Blazar BR, Elliott DE, Ince MN. Helminth-Induced Production of TGF-β and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells. J Immunol. 2018 Nov 15;201(10):2910-2922.
Li Y, Liu W, Guan X, Truscott J, Creemers JW, Chen HL, Pesu M, El Abiad RG, Karacay B, Urban JF Jr, Elliott DE, Kaplan MH, Blazar BR, Ince MN. STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells. J Immunol. 2018 Nov 1;201(9):2612-2623.
Murali AR, Chandra S, Stewart Z, Blazar BR, Farooq U, Ince MN, Dunkelberg J. Graft Versus Host Disease After Liver Transplantation in Adults: A Case series, Review of Literature, and an Approach to Management. Transplantation. 2016 Dec;100(12):2661-2670. Review.
Ince MN, Blazar BR, Edmond MB, Tricot G, Wannemuehler MJ. Understanding Luminal Microorganisms and Their Potential Effectiveness in Treating Intestinal Inflammation. Inflamm Bowel Dis. 2016 Jan;22(1):194-201. doi: 10.1097/MIB.0000000000000599. Review.
Li Y, Chen HL, Bannick N, Henry M, Holm AN, Metwali A, Urban JF Jr, Rothman PB, Weiner GJ, Blazar BR, Elliott DE, Ince MN. Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice. J Immunol. 2015 Feb 1;194(3):1011-20. doi: 10.4049/jimmunol.1303099. Epub 2014 Dec 19
All Publications
See Dr. Ince's complete list of publications at PubMed.