M. Nedim Ince, MD
Clinical Associate Professor of Internal Medicine
Gastroenterology and Hepatology
Welcome
Dr. Ince's clinical interests include general gastroenterology with particular interest in inflammatory bowel disease. His research focuses on intestinal and T helper-2 dependent immune regulation of graft-versus-host disease and inflammatory bowel diseases. His laboratory also investigates the role of T helper 2 pathway in anti-tumor immunity after bone marrow or hematopoietic cell transplantation.
Selected Recent Publications
Truscott J, Guan X, Fury H, Atagozli T, Metwali A, Liu W, Li Y, Li RW, Elliott DE, Blazar BR, Ince MN. After bone marrow transplantation, the cell-intrinsic Th2 pathway promotes recipient T lymphocyte survival and regulates graft-versus-host disease. Immunohorizons. 2023 Jun 1; 7(6):442-455.
Atagozli T, Elliott DE, Ince MN. Helminth lessons in inflammatory bowel diseases (IBD). Biomedicines 2023 Apr 18; 11(4): 1200.
Li Y, Guan X, Liu W, Chen HL, Truscott J, Beyatli S, Metwali A, Weiner GJ, Zavazava N, Blumberg RS, Urban JF Jr, Blazar BR, Elliott DE, Ince MN. Helminth-Induced Production of TGF-β and Suppression of Graft-versus-Host Disease Is Dependent on IL-4 Production by Host Cells. J Immunol. 2018 Nov 15;201(10):2910-2922.
Li Y, Liu W, Guan X, Truscott J, Creemers JW, Chen HL, Pesu M, El Abiad RG, Karacay B, Urban JF Jr, Elliott DE, Kaplan MH, Blazar BR, Ince MN. STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells. J Immunol. 2018 Nov 1;201(9):2612-2623.
Murali AR, Chandra S, Stewart Z, Blazar BR, Farooq U, Ince MN, Dunkelberg J. Graft Versus Host Disease After Liver Transplantation in Adults: A Case series, Review of Literature, and an Approach to Management. Transplantation. 2016 Dec;100(12):2661-2670. Review.
Ince MN, Blazar BR, Edmond MB, Tricot G, Wannemuehler MJ. Understanding Luminal Microorganisms and Their Potential Effectiveness in Treating Intestinal Inflammation. Inflamm Bowel Dis. 2016 Jan;22(1):194-201. doi: 10.1097/MIB.0000000000000599. Review.
Li Y, Chen HL, Bannick N, Henry M, Holm AN, Metwali A, Urban JF Jr, Rothman PB, Weiner GJ, Blazar BR, Elliott DE, Ince MN. Intestinal helminths regulate lethal acute graft-versus-host disease and preserve the graft-versus-tumor effect in mice. J Immunol. 2015 Feb 1;194(3):1011-20. doi: 10.4049/jimmunol.1303099. Epub 2014 Dec 19
All Publications
See Dr. Ince's complete list of publications at PubMed.